Single-cell landscape of the mouse HNSCC-related bone invasive lesion

ABSTRACT: To understand the invasive microenvironment of head and neck squamous cell carcinomas (HNSCCs) at a single-cell resolution, we performed single-cell RNA-sequencing (scRNA-seq) using cells derived from calvaria of tumor-free control mice and tumor-excised calvarial tissues from pre-invasive stage（scratch-negative）and invasive stage（scratch-positive）groups 1 week after the implantation of C57BL/6-derived HNSCC cell line HNM007 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE241334 | GEO | 2024/06/17

REPOSITORIES: GEO