KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance [scRNA-seq]
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ABSTRACT: Immune cells were isolated from the lungs of mice bearing KEAP1 mutant or wildtype tumors. We found that in KEAP1 mutant tumors there is a reduction in CD103 DCs and early activated T cells as well as an increase in exhausted CD8 T cells in comparison to WT controls.
ORGANISM(S): Mus musculus
PROVIDER: GSE241481 | GEO | 2023/11/27
REPOSITORIES: GEO
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