In vitro pigmentation of human iPSC-derived retinal pigment epithelium cells is not indicative of their quality for cell transplantation

ABSTRACT: Retinal pigment epithelium (RPE) cells show heterogeneous level of pigmentation when cultured in vitro. We used Automated Live imaging and cell Picking System (ALPS) with single cell RNA sequencing (scRNA-seq) to analyze the correlation between color intensities and gene expression profiles of human-induced pluripotent stem (iPS) cell-derived RPE cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE242184 | GEO | 2024/05/04

REPOSITORIES: GEO