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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [RNA-Seq_shKD]

ABSTRACT: To investigate the molecular role of CHD9 in prostate cancer, we knockdown CHD9 gene by two different shRNAs in 22Rv1 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE242444 | GEO | 2025/12/15

REPOSITORIES: GEO

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [ATAC-Seq]

Project description:To investigate the molecular role of CHD9 in prostate cancer, we knockdown CHD9 gene by two different shRNAs in 22Rv1 cells.

2025-12-15 | GSE255794 | GEO

METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [ChIP-Seq]

Project description:To investigate the molecular role of CHD9 in prostate cancer, we knockdown CHD9 gene by two different shRNAs in 22Rv1 cells.

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Epitranscriptomic editing screening identifies functional m6A Sites

Project description:This dataset supports the identification of proteins associated with CHD9 by immunoprecipitation-mass spectrometry (IP-MS) in prostate cancer cells. Endogenous CHD9 was enriched using anti-CHD9 antibodies (with IgG controls), and co-enriched proteins were identified by LC-MS/MS. The resulting protein identifications provide a resource to characterize the CHD9 interactome/associated protein complexes in the cellular context examined in the accompanying study.

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers

Project description:This SuperSeries is composed of the SubSeries listed below. GSE242444 GSE242446 GSE255792 GSE255794 GSE312888 GSE312890

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [CRISPR screen_H358]

Project description:In this study, we used a targeted CRISPR/CasRx-METTL3 screen to identify m6A peaks that are critical for prostate and lung cancer.

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [CRISPR screen_22Rv1]

Project description:In this study, we used a targeted CRISPR/CasRx-METTL3 screen to identify m6A peaks that are critical for prostate and lung cancers.

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [RNA-Seq 22Rv1 M3 writing]

Project description:In this study, we used a targeted CRISPR/CasRx-METTL3 screen to identify m6A peaks that are critical for prostate cancer.

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [RNA-Seq 22Rv1 M3 writing]

Project description:METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [RNA-Seq 22Rv1 M3 writing]

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers

Project description:METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers

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METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [CRISPR screen_H358]

Project description:METTL3-based epitranscriptomic editing screening identifies functional m6A sites in cancers [CRISPR screen_H358]