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CpG B and R848 induced gene expression in IRAK2 wildtype and deficient mouse macrophages

ABSTRACT: Compared to wildtype macrophages, IRAK2 deficient macrophages show higher induced gene expression in responsse to CpG B, but not R848 Manuscipt title: The dual function of IRAK2 in TLR9-mediated interfereon and proinflammatory cytokine production

ORGANISM(S): Mus musculus

PROVIDER: GSE24264 | GEO | 2010/09/23

SECONDARY ACCESSION(S): PRJNA132993

REPOSITORIES: GEO

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CpG B and R848 induced gene expression in IRAK2 wildtype and deficient mouse macrophages

Project description:Compared to wildtype macrophages, IRAK2 deficient macrophages show higher induced gene expression in responsse to CpG B, but not R848 Manuscipt title: The dual function of IRAK2 in TLR9-mediated interfereon and proinflammatory cytokine production Bone marrow derived macrophages from wildtype and IRAK2 knockout mouse were stimulated with CpG B or R848 for 2 hours, or untreated.

2010-09-23 | E-GEOD-24264 | biostudies-arrayexpress

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Mus musculus

Project description:CpG B and R848 induced gene expression in IRAK2 wildtype and deficient mouse macrophages

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Microarray analyses using bone marrow-derived macrophages from Batf2−/− and wildtype mice that had been stimulated with R848

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