Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model

ABSTRACT: Alexander disease is a neurodegenerative diseases caused by mutations of GFAP, an astrocyte-specific gene. We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of astrocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE242666 | GEO | 2023/11/12

REPOSITORIES: GEO