Expression data from CaOV3 TET-On cell line with MYCN inducible expression.

ABSTRACT: High-grade serous ovarian cancer (HGSC) is a challenging disease, especially for patients with immunologically 'cold' tumors devoid of tumor-infiltrating lymphocytes (TIL). HGSC exhibits among the highest levels of MYCN transcriptional signature in human cancer, which is strongly linked to diminished features of anti-tumor immunity. We used microarrays to identify genes potentially dysregulated by the oncogene N-MYC in HGSC cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE242747 | GEO | 2023/12/08

REPOSITORIES: GEO