Genomics

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MicroRNA profiling of mouse bone marrow-derived mast cells during mucosal differentiation and IgE-mediated activation


ABSTRACT: The aim of this study was to investigate microRNA expression pattern and its functional relevance on the commitment toward mucosal differentiation and on IgE-mediated activation of mast cells. To identify microRNA genes the expression of which change during the differentiation and activation of murine primary mast cells in vitro, the putative committed progenitors (c-kit+ cells isolated on day 6 from differentiating cultures), immature mast cells (BMMC), mucosal-type mast cells (MMC), and IgE-activated mast cells were compared by Agilent microRNA array.

ORGANISM(S): Mus musculus

PROVIDER: GSE24321 | GEO | 2011/01/01

SECONDARY ACCESSION(S): PRJNA132845

REPOSITORIES: GEO

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