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Defining the mechanisms of action to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank models

ABSTRACT: We used single cell (sc) RNA-seq to analyze responding SM1 melanoma flank tumors and SM1 brain metastases to explore the mechanism of action of the anti-PD-1+LAG-3 and the anti-PD-1+CTLA-4 combination.

ORGANISM(S): Mus musculus

PROVIDER: GSE243281 | GEO | 2023/11/10

REPOSITORIES: GEO

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