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Identification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis

ABSTRACT: Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E response to 50 mM hydrogen peroxide relative to a water-only control.

ORGANISM(S): Moraxella catarrhalis

PROVIDER: GSE24331 | GEO | 2010/12/07

SECONDARY ACCESSION(S): PRJNA132743

REPOSITORIES: GEO

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Identification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis

Project description:Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E response to 50 mM hydrogen peroxide relative to a water-only control. Wild-type cells were exposed to either 50 mM hydrogen peroxide or a water-only control for 15 minutes. RNA was extracted and DNA microarray analysis performed. 4 biologic replicates were studied. One dye swap was included in this series analysis.

2010-12-07 | E-GEOD-24331 | biostudies-arrayexpress

Identification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis: Evaluation of OxyR dependent Genes

Project description:Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E and M. catarrhalis oxyR mutant response to 50 mM hydrogen peroxide.

2010-12-07 | GSE24351 | GEO

Identification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis: Evaluation of OxyR dependent Genes

Project description:Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E and M. catarrhalis oxyR mutant response to 50 mM hydrogen peroxide. Wild-type cells and oxyR mutant cells were exposed to 50 mM hydrogen peroxide for 15 minutes. RNA was extracted and DNA microarray analysis performed. 4 biologic replicates were studied. One dye swap was included in this series analysis. Control oxyR mutant cells exposed to water

2010-12-07 | E-GEOD-24351 | biostudies-arrayexpress

Global gene expression in Moraxella catarrhalis ATCC 43617 grown under iron-replete and iron-limiting conditions

Project description:Total RNA samples were isolated from M. catarrhalis grown in BHI (iron-replete condition, designated DF0) and in BHI containing 30 mM Desferal (iron-limiting condition, designated DF30). Total RNA and M. catarrhalis genome-directed primers (GDPs) were used for synthesis of Cy3- or Cy5-labeled cDNA samples. Three independent M. catarrhalis growth experiments and total RNA isolations were used for synthesis of cDNA samples, and a total of six DNA microarray hybridizations were performed in this study. Keywords: Effect of Growth Environment on Global Gene Expression by Moraxella catarrhalis

2007-12-07 | GSE4346 | GEO

Identification of gene products involved in the oxidative stress response of Moraxella catarrhalis.

Project description: Not available

| S-EPMC3028835 | biostudies-literature

Deciphering the genetic basis of Moraxella catarrhalis complement resistance: Gene expression analysis of Moraxella catarrhalis BBH18 upon exposure to normal human serum.

Project description:The complement system is an important part of the innate defense against invading pathogens. The ability to resist complement-mediated killing is considered to be an important virulence trait for the human-restricted respiratory tract pathogen M. catarrhalis, as most disease-associated M. catarrhalis isolates are complement-resistant. Here we studied the molecular basis of M. catarrhalis complement-resistance by transcriptome profiling upon exposure to 10% normal human serum (NHS).

2014-06-23 | GSE52552 | GEO

Analysis of the Zur Regulon of Moraxella catarrhalis

Project description:This series of microarrays explores the genes regulated by the Zur gene of Moraxella catarrhalis.

2014-03-23 | GSE28151 | GEO

Moraxella catarrhalis

Project description:Moraxella catarrhalis Genome sequencing

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Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

Project description:Comparison of the gene expression profile of Moraxella catarrhalis grown in the presence of 20% pooled human sputum in chemically-defined medium relative to Moraxella catarrhalis grown in chemically-defined medium alone.

2014-02-02 | GSE27059 | GEO

Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

2014-02-02 | GSE27059 | GEO

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