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Expression data from ETO2 knockdown G1E-ER-GATA-1 cells

ABSTRACT: We used microarrays to examine what genes could be regulated by ETO2 in erythroid cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE24333 | GEO | 2010/09/25

SECONDARY ACCESSION(S): PRJNA133483

REPOSITORIES: GEO

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Expression data from ETO2 knockdown G1E-ER-GATA-1 cells

Project description:We used microarrays to examine what genes could be regulated by ETO2 in erythroid cells. Comparing expression profile in murine G1E-ER-GATA-1 cells treated with control and ETO2(Cbfa2t3) siRNA on Agilent array. After siRNA transfection, the cells were treated with b-estradiol for 24h to induce GATA-1-mediated erythroid maturation.

2010-09-25 | E-GEOD-24333 | biostudies-arrayexpress

Expression data from ETO2/LMO2 knockdown G1E-ER-GATA-1 cells

Project description:This SuperSeries is composed of the following subset Series: GSE24333: Expression data from ETO2 knockdown G1E-ER-GATA-1 cells GSE24336: Expression data from LMO2 knockdown G1E-ER-GATA-1 cells Refer to individual Series

2010-09-25 | E-GEOD-24359 | biostudies-arrayexpress

Expression data from LMO2 knockdown G1E-ER-GATA-1 cells

Project description:We used microarrays to examine what genes could be regurated by LMO2 in erythroid cells.

2010-09-25 | GSE24336 | GEO

Expression data from LMO2 knockdown G1E-ER-GATA-1 cells

Project description:We used microarrays to examine what genes could be regurated by LMO2 in erythroid cells. Comparing expression profile in murine G1E-ER-GATA-1 cells treated with control and Lmo2 siRNA on Agilent array. After siRNA transfection, the cells were treated with b-estradiol for 24h to induce GATA-1-mediated erythroid maturation.

2010-09-25 | E-GEOD-24336 | biostudies-arrayexpress

Expression data from ETO2/LMO2 knockdown G1E-ER-GATA-1 cells

Project description:Expression data from ETO2/LMO2 knockdown G1E-ER-GATA-1 cells

| PRJNA132817 | ENA

Expression data from ETO2/LMO2 knockdown G1E-ER-GATA-1 cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2010-09-25 | GSE24359 | GEO

Location of NFIA-ETO2 binding site on genome in MEL cells

Project description:The NFIA-ETO2 fusion is the product of a t(1;16)(p31;q24) chromosomal translocation so far exclusively found in pediatric patients with pure erythroid leukemia (PEL). To address its role for the pathogenesis of the pure erythroid leukemia, we retrovirally expressed the PEL-associated NFIA-ETO2 fusion in MEL cells. To better identify direct target gene loci, we sequenced NFIA-ETO2-associated immunoprecipitated chromatin and histone modifications.

2023-02-09 | GSE205397 | GEO

Foxo3 Regulated Genes in G1E-ER-GATA-1 Cells

2014-08-09 | GSE60137 | GEO

Effect of NFIA-ETO2 gene fusion on MEL cells during proliferation and impaired erythroid differentiation.

Project description:The NFIA-ETO2 fusion is the product of a t(1;16)(p31;q24) chromosomal translocation so far exclusively found in pediatric patients with pure erythroid leukemia (PEL). To address its role for the pathogenesis of the pure erythroid leukemia, we retrovirally expressed the PEL-associated NFIA-ETO2 fusion in MEL cells. Gene expression was determined by RNA sequencing from MEL cells which express or not NFIA-ETO2.

2023-02-09 | GSE205407 | GEO

Foxo3 Regulated Genes in G1E-ER-GATA-1 Cells

Project description:The ensemble of Foxo3-regulated genes in the erythroid G1E-ER-GATA-1 cell line was determined by knocking down Foxo3 using siRNA, and measuring genome wide transcription by microarray analysis G1E-ER-GATA-1 cells were treated with control or Foxo3-specific siRNA by nucleofection at t = 0 h and t = 24 h. At t = 24 h, cells were treated with M-CM-^_-estradiol to activate ER-GATA-1. RNA was harvested at t = 48 h and processed for microarray analysis.

2014-08-09 | E-GEOD-60137 | biostudies-arrayexpress

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