Switching of OAS1 splicing isoforms mitigates SARS-CoV-2 infection

ABSTRACT: We aimed to study impact of CDC-like kinase (CLK) inhibitor CaNDY on OAS1 splicing manipulation. Our data indicates CaNDY treatment induces switching of OAS1 splice isoforms to provide an increased resistance to SARS-CoV-2 infection.

ORGANISM(S): Homo sapiens

PROVIDER: GSE244026 | GEO | 2025/03/12

REPOSITORIES: GEO