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Spatial transcriptomics reveals heterogeneity of odontogenic keratocysts

ABSTRACT: To reveal the heterogeneity of odontogenic keratocysts (OKCs), we performed spatial transcriptomics (ST) sequencing on two OKC samples. We identified twenty-one cell clusters located in two ST samples through differential gene expression, spatial location information, and Cell2location algorithm combined with single-cell RNA sequencing analysis. The heterogeneity of OKC was revealed through functional enrichment analysis, thereby confirming our hypothesis and laying the foundation for a better understanding of the biological behavior of OKC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE244398 | GEO | 2026/09/30

REPOSITORIES: GEO

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