UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

ABSTRACT: To better understand the impact of Ufl1 expression in T cells on regulating tumor microenvironment dynamics, we performed single-cell RNA sequencing on purified CD45+ immune cells from MC38 xenografts harvested from Ufl1 cKO or WT C57BL/6 mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE244447 | GEO | 2024/01/30

REPOSITORIES: GEO