Transcriptomics

Dataset Information

0

State-transition Modeling of Blood Transcriptome Predicts Disease Evolution and Treatment Response in Chronic Myeloid Leukemia (CML)


ABSTRACT: Chronic myeloid leukemia (CML) is initiated and initially maintained solely by the fusion gene BCR-ABL, encoding a mutant protein targeted in the clinic with tyrosine kinase inhibitors (TKIs) While TKI treatment is effective in inducing long-term remission, frequently is not curative. For these reasons, CML is an ideal disease to test our hypothesis that that transcriptome-based state-transition models accurately predict cancer evolution and treatment response. We hypothesized that transcriptome-based state-transition models accurately predict cancer evolution and treatment response.

ORGANISM(S): Mus musculus

PROVIDER: GSE244990 | GEO | 2023/11/02

REPOSITORIES: GEO

Similar Datasets

2016-12-21 | GSE92624 | GEO
2021-04-13 | GSE171945 | GEO
2016-12-15 | GSE85903 | GEO
2018-01-20 | E-MTAB-2594 | biostudies-arrayexpress
2024-01-01 | E-MTAB-11896 | biostudies-arrayexpress
2024-01-01 | E-MTAB-11899 | biostudies-arrayexpress
2023-11-15 | GSE226360 | GEO
2020-04-23 | GSE133642 | GEO
2016-08-18 | GSE85744 | GEO
2023-06-23 | GSE230534 | GEO