Transcriptomics

Dataset Information

27

Pten signaling in fibroblasts effects gene expression in endothelial and epithelial cells


ABSTRACT: These experiments aim determine the effects of Pten signaling in fibroblasts on gene expression in other cell compartments in the mammary gland. Overall design: To achieve this, we used a genetic model in which the tumor suppressor gene Pten was specifically inactivated in stromal fibroblats. We then isolated fibroblasts, epithelial cells and endothelial cells from the mammary glands of mice with either wild type or Pten null fibroblasts. Comparisons were made between wild type and Pten counterparts, not between the various cell types.

INSTRUMENT(S): [MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [transcript (gene) version]

ORGANISM(S): Mus musculus  

SUBMITTER: Julie Wallace  

PROVIDER: GSE24501 | GEO | 2011-12-18

SECONDARY ACCESSION(S): PRJNA132605

REPOSITORIES: GEO

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