Irinotecan activates anti-tumor immunity in CT26 subcutaneous tumors

ABSTRACT: Topoisomerase I (Top1) is a classical drug target for anticancer therapy, but its role in immune signaling in cancer cells remain unclear. Here, we aimed to explore the possible role and mechanism of Irinotecan (CPT-11) in anti-tumor immunity.

ORGANISM(S): Mus musculus

PROVIDER: GSE245431 | GEO | 2025/10/16

REPOSITORIES: GEO