Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE245643 | GEO | 2025/07/05

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression

Project description:Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression

| PRJNA1029485 | ENA

MOF-associated complexes ensure stem cell identity and Xist repression

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-06-03 | E-GEOD-57701 | biostudies-arrayexpress

DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects

Project description:This SuperSeries is composed of the SubSeries listed below.

2025-02-14 | GSE209843 | GEO

Domains of genomewide gene expression dysregulation in Down syndrome

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-04-08 | E-GEOD-55426 | biostudies-arrayexpress

Xist upstream deletion impairs topological contacts of Xist locus and affects Xist coating/expression and autosomal gene expression [4C]

Project description:In this study, we have investigated the role of Xist upstream region located near the Xist-TAD boundary in maintenance of imprinted X-chromosome inactivation in extraembryonic endoderm stem cells (XEN). We found that deletion of Xist upstream region(~6Kb) leads to the alterations of Xist intra-TAD contacts and upregulate Xist expression. Moreover, it impaired the interactions of the Xist locus across X-chromosomes and autosomes. Moreover, Xist upstream deletion resulted dispersal of Xist coating and loss of accumulation of diffrent repressive chromatin marks on the inactive-X. Surprisingly there was no effect on inactive-X gene silencing, however, it affeted the autosomal gene expression.

2025-07-07 | GSE245642 | GEO

Dysregulation of Endometrial Inflammation Precedes the Development of Cytological Endometritis

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-08-01 | E-GEOD-66827 | biostudies-arrayexpress

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2016-03-02 | E-GEOD-76292 | biostudies-arrayexpress

LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-27 | E-GEOD-67336 | biostudies-arrayexpress

Transcription repression of miR-221 leads to p27 expression in PEL

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series