Bulk RNA-sequencing of mouse prostate tumors initiated by transplantation of engineered organoids.

ABSTRACT: Purpose: Profile global expression of prostatic tumors to compare with published datasets. Methods: Prostate tumors were flash frozen followed by processed for total RNA using the RNeasy kit (Qiagen). Samples were submitted for polyA library preparation and bulk RNA-sequencing. Conclusions: Global gene expression profiling and comparison of prostate tumor genotypes suggests differential enrichment of neuroendocrine signatures that match established human neuroendocrine prostate cancer expression signatures.

ORGANISM(S): Mus musculus

PROVIDER: GSE246251 | GEO | 2024/08/02

REPOSITORIES: GEO