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Effect of CSPTTK21 on 12 month-old Thy-Tau22 mice, hippocampal samples (ChIP H3K27ac)

ABSTRACT: This project aims to identify epigenetic signatures (histone acetylation-related) associated with Tau pathology in hippocampal region of Thy-Tau22 mice in basal conditions and after treatment with CSP-TTK21. For this we performed ChIP for H3K27ac in whole hippocampus of 12 month-old Tau reated with the vehicle CSP or CSP-TTK21, as well as of CSP-treated 12 month-old WT mice.In total we have 6 IPed samples (Biological duplicates were analyzed) and 3 Inputs. Spike-in from drosophila chromatin was added to the samples.

ORGANISM(S): Mus musculus

PROVIDER: GSE246773 | GEO | 2025/06/04

REPOSITORIES: GEO

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