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ScRNA-seq of control and Etv1 mutant distal small intestinal organoid cultures

ABSTRACT: To characterize the effect of mutating Etv1 on enteroendocrine cell specification and hormone expression, we performed scRNA-seq experiments analysing cells from control and Etv1 mutant organoid cultures from mouse distal small intestine. We identified 6 transcriptionally distinct clusters, that had a similar cellular contribution from controls and Etv1 mutants. In the cluster identified as enteroendocrine cells, we observed differences in hormone expression between controls and Etv1 mutants.

ORGANISM(S): Mus musculus

PROVIDER: GSE247349 | GEO | 2025/11/01

REPOSITORIES: GEO

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