Overcoming resistance to anti-VEGF therapy via epigenetic regulation of BARD1 [methylation]

ABSTRACT: Genome wide DNA methylation profiling of anti-VEGF resistant SKOV3 tumor samples treated with B20 and/or Azacytidine. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 450,000 CpGs in SKOV3 tumors. Samples included 2 control IgG, 2 Azacytidine, 2 B20 and 2 B20+Azacytidine treated SKOV3ip1 tumors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE247655 | GEO | 2025/06/17

REPOSITORIES: GEO