Transcriptomics

Dataset Information

20

Gene expression data of BCR-ABL1 transformed myeloid cells from BCL6 wild-type and BCL6 knockout mice treated with and without Imatinib and RI-BPI


ABSTRACT: To identify differences in the gene regulation between BCL6+/+ and BCL6-/- CML cells a gene expression analysis has been performed. We investigated the gene expression pattern in BCL6+/+ cells in the presence or absence of Imatinib and a combination of Imatinib and RI-BPI (a novel retro-inverso BCL6 peptide inhibitor). In BCL6-/- CML cells, we investigated the gene expression pattern in the presence or absence of Imatinib. Overall design: BCR-ABL1 transformed myeloid cells from BCL6+/+ mice were cultured in the presence or absence of 10µM Imatinib or 10µM Imatinib and 20µM RI-BPI for 16 hours. BCR-ABL1 transformed myeloid cells from BCL6-/- mice were cultured in the presence or absence of 10µM Imatinib. Two samples for each condition were processed.

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

ORGANISM(S): Mus musculus  

SUBMITTER: Markus Müschen   

PROVIDER: GSE24813 | GEO | 2011-08-24

SECONDARY ACCESSION(S): PRJNA132311

REPOSITORIES: GEO

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2011-09-06 | E-GEOD-24813 | ArrayExpress
2011-03-01 | E-GEOD-24381 | ArrayExpress
| GSE24381 | GEO
2015-10-01 | E-GEOD-20987 | ArrayExpress
| GSE20987 | GEO
2015-09-15 | E-GEOD-20987 | ExpressionAtlas
| GSE24404 | GEO
2014-05-02 | E-GEOD-24404 | ArrayExpress
2010-09-21 | GSE24236 | GEO
2014-05-02 | E-GEOD-24236 | ArrayExpress