PIK3CA and KRAS codon-specific mutations differentially toggle pathway activity and alter sensitivity to inavolisib (GDC-0077)
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ABSTRACT: To explore the single and combinatorial effect of MEK and PI3KCA inhibitors in CRC lines with PIK3CA/KRAS mutations, we used the MULTI-seq CMOs to perform a highly multiplexed single-cell RNA-seq.
ORGANISM(S): Homo sapiens
PROVIDER: GSE248412 | GEO | 2025/06/15
REPOSITORIES: GEO
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