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Spatial profiling of synovial tissue from patients with late-stage knee osteoarthritis.

ABSTRACT: Marked changes in synovial tissue are seen in knee osteoarthritis and are related to pain; however, the regulation of these processes are not fully understood. Spatial profiling was used to characterize cellular profiles and biological processes within important microenvironments in the synovium (intimal lining, sub-lining, and vessels) between patients that experience more pain compared to those that experience less pain.

ORGANISM(S): blank sample Homo sapiens

PROVIDER: GSE248454 | GEO | 2025/04/21

REPOSITORIES: GEO

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