Transcriptomics

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Single cell transcriptome analysis of Cyfip2 knockout mouse forebrain


ABSTRACT: To elucidate the intricate molecular alterations resulting from Cyfip2 knockout, we conducted single cell transcriptomic analysis on the forebrain tissues of E18.5 Cyfip2 knockout mice and their wild-type littermates. The E18.5 stage was selected due to the nonviability of Cyfip2 knockout mice during the perinatal period. Cyfip2 knockout and wild-type mice were obtained by breeding Cyfip2 heterozygous males and females. For each genotype, we combined the forebrains from two mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE248722 | GEO | 2026/01/22

REPOSITORIES: GEO

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