Glucocorticoid Receptor cistromic reprogramming by caloric restriction and corticosterone treatments.

ABSTRACT: In order to examine the impact of two separate corticosterone surges on liver physiology, we conducted genome-wide mapping of GR binding profiles at 6 pm (ZT12) through ChIP-sequencing. This was done using liver samples from mice subjected to either short-term caloric restriction or corticosterone injections. Our findings reveal that both interventions yield unique binding profiles.

ORGANISM(S): Mus musculus

PROVIDER: GSE248865 | GEO | 2025/11/04

REPOSITORIES: GEO