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Expression profile of early stage in OKS mediated reprogramming regulated by Sox2 and Klf4

ABSTRACT: Klf4 and Sox2 are among the core reprogramming factor, and have different function in reprogramming. Klf4 is supposed to trigger MET in the early stage of reprogramming ,Sox2 is well known plutipotent relative gene. Klf4 and Sox2 play important role in induced reprogramming. We performed this experiment to identify the targets regulated by Sox2 and Klf4 respectively.

ORGANISM(S): Mus musculus

PROVIDER: GSE24929 | GEO | 2010/10/27

SECONDARY ACCESSION(S): PRJNA133465

REPOSITORIES: GEO

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Gene expression analysis during reprogramming with sequential infecion of Oct4/Klf4/cMyc/Sox2

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Cooperative binding of Oct4, Sox2, and Klf4 with stage-specific transcription factors orchestrates reprogramming [ATAC-seq]

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