Non-canonical AMPA receptor blockade reduces lymph node egress and neuroinflammation [scRNA-seq]

ABSTRACT: Disturbances in the glutamatergic system have been linked to neuronal pathology. Investigating therapeutic translation, we discovered immune-related effects for the selective non-competitive AMPA receptor blocker perampanel in mouse models of multiple sclerosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE249327 | GEO | 2025/06/13

REPOSITORIES: GEO