Molecular targets of the NEDD8 activating enzyme inhibitor TAS4464 in CD4+ T cells from HTLV-1-infected asymptomatic carriers.

ABSTRACT: Adult T-cell Leukemia (ATL) is a highly chemoresistant malignancy of peripheral T lymphocytes, associated with retrovirus human T-cell leukemia virus type I (HTLV-1). To elucidate the complex molecular mechanism of anti-Growth effect of the NEDD8 activating enzyme inhibitor TAS4464 in HTLV-1-infected cells, we attempted to perform single-cell RNA sequence profiling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE250517 | GEO | 2024/04/01

REPOSITORIES: GEO