Single-cell sequencing reveals cellular heterogeneity of nucleus pulposus in intervertebral disc degeneration

ABSTRACT: Nucleus pulposus (NP) plays a vital role in intervertebral disc degeneration (IVDD). Previous studies have revealed cellular heterogeneity in the NP tissue during IVDD progression. Here, we used single cell RNA sequencing (scRNA-seq) to analyze the cellular and molecular alterations of diverse cell clusters during IVDD.

ORGANISM(S): Homo sapiens

PROVIDER: GSE251686 | GEO | 2024/11/14

REPOSITORIES: GEO