Effect of ASB2 deletion on gene expression in non-stimulated and stimulated mouse Th2 lymphocytes

ABSTRACT: Because ASB2a-mediated degradation of filamin A and filamin B could be involved in the modulation of Th2 lymphocyte signaling and thus in the regulation of Th2-specific genes, the transcriptomic signatures of ctrl and ASB2a-deficient Th2 lymphocytes were established by RNA-seq. We here report no impact of ASB2a loss and filamin A/filamin B accumulation on the transcriptomic program of Th2 lymphocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE251847 | GEO | 2024/09/23

REPOSITORIES: GEO