Transcriptomics

Dataset Information

0

High-content phenotypic analysis defines generalizable genetic and molecular regulators of lifespan in a C. elegans recombinant inbred population


ABSTRACT: Background and Aims: Lifespan is influenced by complex interactions between genetic and environmental factors. Limitations in studying those factors in model organisms of a single genetic background hinder translational value. Here, we mapped genetic determinants of lifespans in 85 C. elegans recombinant intercross advanced inbred lines (RIAILs). We assessed molecular profiles – transcriptome, proteome, and lipidome – and life-history traits (lifespan), development, growth dynamics, and reproduction.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE252593 | GEO | 2024/02/07

REPOSITORIES: GEO

Similar Datasets

2023-10-12 | GSE205228 | GEO
2011-04-01 | GSE21562 | GEO
2017-07-07 | PXD006613 | Pride
2011-04-01 | E-GEOD-21562 | biostudies-arrayexpress
2021-11-07 | GSE188294 | GEO
2014-10-02 | GSE58778 | GEO
2020-07-13 | GSE124294 | GEO
2021-12-23 | GSE191320 | GEO
2017-05-31 | GSE99440 | GEO
2012-03-28 | GSE36838 | GEO