SoxB1 transcription factors are essential for intiating and maintaining neural plate border gene expression [ChIP-seq]

ABSTRACT: Here we investigate a functional role for SoxB1 transcription factors, Sox2 and Sox3, on the transient embryonic cell population, the neural plate border. We find through gain/loss-of-function studies necessary for neural plate border cells to become neural crest cells. and genomics experiments (ChIP-seq and RNA-seq) that SoxB1 transcription factors directly promote neural plate border formation. and that down-regulation of SoxB1 expression is

ORGANISM(S): Xenopus laevis

PROVIDER: GSE252615 | GEO | 2024/06/26

REPOSITORIES: GEO