Transcriptomics

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Malaria parasite manipulates erythrocyte membranes for intracellular adaptation : RNA-seq


ABSTRACT: The ability to respond to stressful host environments is crucial for the survival of intracellular pathogens, during which transporters play key roles in the nutrient scavenging, such as lipid uptake. Here we discover a conserved malarial gene that orchestrates the parasitic adaption in the terminally differentiated, phospholipid scarce erythrocytes. The expression level of this gene, here named CAP, is the intensively upregulated in the erythrocyte-infecting parasites than the reticulocyte-infecting counterparts.

ORGANISM(S): Plasmodium berghei

PROVIDER: GSE252704 | GEO | 2026/07/01

REPOSITORIES: GEO

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