Autosomal dominant gain-of-function mutations in LCP1 cause syndromiceneutropenia and immunodeficiency-

ABSTRACT: To further evaluate the impact of LCP1 dysfunction on hematopoiesis, we performed single-cell RNA sequencing (scRNA-seq) for bone marrow cells from patients and two matched healthy controls. Total 39, 028 cells were included in the sequential analysis after quality control.

ORGANISM(S): Homo sapiens

PROVIDER: GSE252973 | GEO | 2026/03/01

REPOSITORIES: GEO