Evaluation of PFHpA impact on liver metabolism using human liver spheroids

ABSTRACT: Accumulating evidence suggests that poly- and perfluoroalkyl substances (PFAS), a class of persistent organic pollutants, cause changes in hepatic lipid, amino acid, and glucose metabolism. Our study explores the molecular mechanisms whereby PFHpA disrupts liver metabolism and facilitate NAFLD development.

ORGANISM(S): Homo sapiens

PROVIDER: GSE253186 | GEO | 2025/09/18

REPOSITORIES: GEO