Lifestyle-induced changes in alternative splicing patterns in mice [adipose]

ABSTRACT: Alternative splicing diversifies the cellular protein landscape but aberrant splicing is implicated in many diseases. We aimed to investigate to which extent mis-splicing contributes to insulin resistance as the causal defect of Type 2 Diabetes and whether diet- and exercise-based lifestyle interventions can reverse mis-splicing.

ORGANISM(S): Mus musculus

PROVIDER: GSE253219 | GEO | 2025/03/03

REPOSITORIES: GEO