Genomics

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Effects of renal ischemia-reperfusion injury in Azin1 A-to-I locked and uneditable mice


ABSTRACT: We generated two mouse models of Azin1 A-to-I editing. In the first model, the editing site is locked in the edited state (AGC serine to GGC glycine). In the second model, the editing site is disrupted while preserving the codon composition (AGC serine to TCC serine). Bulk total RNA-seq was performed on kidney tissues under basal conditions and 24 hours after 20 min bilateral renal ischemia-reperfusion injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE253286 | GEO | 2024/01/20

REPOSITORIES: GEO

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