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Single-cell RNA-sequencing from stroma in a mouse submandibular salivary gland following 14-day ligation or mock surgery

ABSTRACT: The submandibular salivary gland stroma makes up only a small portion of the total salivary gland and the stromal response to salivary gland injury has been understudied. We used single-cell RNA-sequencing (scRNAseq) to analyze which cell types are present in ductal ligated and mock surgery salivary glands, how the cell type abundance is altered during injury, and how the transcriptome of those cells is being altered. This will allow us to examine which cell types are important contributors to recovery from salivary gland ductal ligation injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE253916 | GEO | 2024/01/23

REPOSITORIES: GEO

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