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IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [I]

ABSTRACT: To further understand the downstream mechanism of IL17/IL17R signaling in tumor cells, we performed transcriptome sequencing analysis of 4T1 cells treated with rIL17A

ORGANISM(S): Mus musculus

PROVIDER: GSE254146 | GEO | 2024/11/14

REPOSITORIES: GEO

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IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [II]

Project description:To further understand the downstream mechanism of IL17/IL17R signaling in tumor cells, we performed transcriptome sequencing analysis of 4T1 cells treated with rIL17A

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IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [I]

Project description:IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [I]

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IL17A-induced OPN from tumor cells promotes tumor progression by inducing tissue-resident TAM proliferation via LYVE1 [II]

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microRNA expression during tumor-associated macrophage (TAM) differentiation

Project description:To further analyze the change of microRNA(miRNA) between normal peritoneal macrophage(PEC) and TAM from early tumor(12 days after 4T1 cell injection) or TAM from late tumor(21 days after 4T1 cell injection) , we employed Agilent mouse microRNA microarray Rel 12.0 as a discovery platform to identify miRNAs Total RNA from peritoneal macrophage and TAM of early tumor (tumor formed for 12days after BALB/c mice injected wth 4T1 cell) or TAM of late tumor(tumor formed for 21days after BALB/c mice injected with 4T1 cell) were extracted and analyzed using Agilent mouse microRNA microarray platform, and changes of miRNA were screened out. Agilent mouse microRNA microarray is designed for the profiling of mouse miRNA .627 mouse miRNA and 39 mouse virus-related miRNA can be detected by our microRNA microarray.

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