Mapping the gecko chromatin accessibility landscape by UUATAC-seq

ABSTRACT: The current understanding of regulatory sequences in the vertebrate genome is still incomplete. By introducing an adapter switching strategy, we developed an ultra-throughput ultra-sensitivity single-nucleus ATAC-seq (UUATAC-seq) protocol that enables construction of high-quality chromatin accessibility landscape from one species in a one-day experiment. By using UUATAC-seq, we mapped open chromatin regions for five representative vertebrate species at the landscape scale.

ORGANISM(S): Eublepharis macularius

PROVIDER: GSE254159 | GEO | 2025/07/14

REPOSITORIES: GEO