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Dynamic fibroblast-immune interactions shape recovery after brain injury [Visium]


ABSTRACT: Fibroblasts and immune cells coordinate tissue regeneration and necessary scarring after injury. In the brain, fibroblasts are border-enriched cells whose dynamic molecular states and immune interactions after injury remain unclear. We used spatial transcriptomics (10X Visium) to spatiotemporally profile CNS wound healing responses, including stromal and immune responses, after photothrombotic (PT) injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE254161 | GEO | 2025/06/30

REPOSITORIES: GEO

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