Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer [Hi-C]

ABSTRACT: To investigate the Nexturastat A effects on chromatin structure which disrupt phospho-HDAC6 LLPS in triple-negative breast cancer (TNBC), we conducted the analysis of Hi-C in TNBC cells treated with or without Nexturastat A.

ORGANISM(S): Homo sapiens

PROVIDER: GSE254213 | GEO | 2024/05/09

REPOSITORIES: GEO