Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm [ATAC-seq]

ABSTRACT: We discovered a role for the transcription factor OTX2 in formation of mouse definitive endoderm (DE). We used ATAC-seq to identify open chromatin regions in OTX2-depleted definitive endoderm cells and identify sites with changed accessibility during DE differentiation

ORGANISM(S): Mus musculus

PROVIDER: GSE254431 | GEO | 2024/06/26

REPOSITORIES: GEO