The Hxk1 protein of Candida albicans influences gene expression of both metabolic and virulence related genes

ABSTRACT: The Hxk1 protein of Candida albicans is a moonlighting protein with a wide variety of functions. It phosphorylates N-acetylglucosamine (GlcNAc) which is necessary for different purposes in the cell including energy and chitin production. Further, this protein is a regulator for morphogenesis independent of its function during GlcNAc catabolism.To identify the regulatory role of Hxk1 and putative downstream regulator Hxk2, we performed CUT&RUN experiments for GFP-tagged Hxk1 strains and GFP-tagged Hxk2 strains.

ORGANISM(S): Candida albicans

PROVIDER: GSE254730 | GEO | 2024/02/13

REPOSITORIES: GEO