Changes in chromatin accessibility in intratumoral CD8+ T cell subsets between young and aged TME

ABSTRACT: Here, we present genome-wide comparisons of chromatin accessibility from endogenous CD8+ T cells and transferred OT-1 CD8+ T cells in young vs. aged B16-OVA tumors using ATAC-seq. This ATAC-seq dataset includes three different intratumoral CD8+ T cell subsets, such as TProg: Slamf6+Tim-3-, TTerm: Slamf6-Tim-3+, and TTAD: Slamf6-Tim-3-, as well as naive CD8+ T cells from spleens.

ORGANISM(S): Mus musculus

PROVIDER: GSE255230 | GEO | 2024/03/14

REPOSITORIES: GEO