Ontology highlight
ABSTRACT:
INSTRUMENT(S): GLYCOv1 glycogene array
SUBMITTER: Jennifer A Hammond
PROVIDER: GSE2554 | GEO | 2005-05-03
SECONDARY ACCESSION(S): PRJNA92163
REPOSITORIES: GEO
Comelli Elena M EM Sutton-Smith Mark M Yan Qi Q Amado Margarida M Panico Maria M Gilmartin Tim T Whisenant Thomas T Lanigan Caroline M CM Head Steven R SR Goldberg David D Morris Howard R HR Dell Anne A Paulson James C JC
Journal of immunology (Baltimore, Md. : 1950) 20060801 4
Differentiation and activation of lymphocytes are documented to result in changes in glycosylation associated with biologically important consequences. In this report, we have systematically examined global changes in N-linked glycosylation following activation of murine CD4 T cells, CD8 T cells, and B cells by MALDI-TOF mass spectrometry profiling, and investigated the molecular basis for those changes by assessing alterations in the expression of glycan transferase genes. Surprisingly, the maj ...[more]