Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs [ChIP-Seq]
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ABSTRACT: Through a multi-omics approach, we discovered that metformin acts by enhancing the methylation potential in Dnmt3aR878H/+ cells and reversing their aberrant DNA CpG methylation and histone H3K27 trimethylation (H3K27me3) profiles.
ORGANISM(S): Mus musculus
PROVIDER: GSE255550 | GEO | 2025/02/07
REPOSITORIES: GEO
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