Effects of lipopolysaccharide (LPS) or interferon gamma (IFNy) treatment on wild type or PILRA knock-out iPSC-derived human microglia after 24 hours

ABSTRACT: To study the effect of PILRA loss-of-function immune signaling pathways, we treated wildtype and PILRA knock-out (KO) iPSC-derived microglia (iMGs) with lipopolysaccharide (LPS) or interferon gamma (IFNy) for 24 hours and performed bulk RNA-seq analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE255658 | GEO | 2025/11/20

REPOSITORIES: GEO